Colby and Casey Rasmus faced each other in a Major League game on May 28, with Colby (with Blue Jays) hitting a double off brother Cory (with Braves). Another brother, Casey is currently in the Cardinals organization. A fourth brother, Cyle, played baseball collegiately. These four brothers followed in the footsteps of their father, Anthony, who played minor league baseball in the Angels organization from 1986 to 1988.
See story in The Globe and Mail about the Rasmus brothers in the below link: